Mrmed Pharmacy

  Seborrheic dermatitis is the most common inflammatory skin condition, which presents as scaly patches and red skin on the oily areas of the body, such as the scalp, face, sides of the nose, eyebrows, ears, eyelids, and chest. Usually, this condition fades away on its own in infants and some adults. If the symptoms don’t subside, there are many effective proactive strategies mentioned below to manage the symptoms and to stop seborrheic dermatitis from flaring up in the future. Prevalence and Etiology Seborrheic dermatitis is most commonly seen in infants and adults between 30 and 60, but it can affect people of any age. Studies say that 3–10 people in every 100-experience seborrheic dermatitis during their lifetime. Seborrheic dermatitis is not a contagious infection, meaning you can’t get it from another person. Usually, it is due to certain genetic and environmental factors that trigger the condition. Common factors that cause seborrheic dermatitis include: Stress Hormonal chang...

Bevacizumab is a recombinant monoclonal antibody that blocks the growth of new blood vessels (angiogenesis). It is often used in the treatment of various advanced cancers. It is developed to prevent the growth of tumors. It is indicated along with other chemotherapy drugs to treat metastatic breast cancer, brain cancer, cervical cancer, kidney cancer, lung cancer, and colorectal cancer. It is also used to treat cancers of the ovary, fallopian tube, or primary peritoneal cancer. It is not recommended for children under the age of 18. How Does Bevacizumab work It is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A), which is present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that su...

Tacrolimus is an active ingredient belonging to the class of immunosuppressants, which subsequently works by suppressing the actions of immune cells and the immune system of the body. It is useful in situations where the body rejects new organs like lungs, liver, or kidneys after an organ transplant. Prograf 1mg capsule is a brand that contains the active compound tacrolimus that delivers a therapeutic effect.  Indications: Prevention of organ rejection in recipients of allogeneic heart, kidney, or liver transplants It can be used along with adrenal corticosteroids in prophylactic treatment approaches in kidney, liver, and lung transplants. Mechanisms involved in preventing organ rejection:  Tacrolimus acts through a cascade of events that involve effective immune suppression. An enzyme called calcineurin is involved in the activation of T cells which is essential for producing basic immune responses against the inflammations. Tacrolimus blocks and inhibits the activity of th...

Hemolytic disease of the newborn: Rhesus factor is a kind of protein occurring on the surface of red blood cells; every individual is born with either present (positive Rh type) or absent ( negative Rh type) Rh typing. Hemolytic disease is the blood disorder that occurs in newborn infants when the Rhesus factor (positive or negative ) in the blood group becomes incompatible between the mother and baby. Rhesus factor incompatibility occurs when an Rh-negative mother carries an Rh-positive fetus, causing hemolytic disease.   The immune system of the mother identifies the Rh-positive red blood cells of the fetus as a foreign body. It produces antibodies to destroy the red blood cells. In other words, hemolytic disease refers to the breakdown of red blood cells in infants, also referred to as erythroblastosis fetalis. (breaking down of red blood cells in the fetus) The immune system thus keeps a memory of this encounter during the first pregnancy, and the mother becomes Rh-sensitized, ...

Ergosterol is an important element of the cellular membrane in fungi, playing a role much like cholesterol in animal cells. Inhibitors of fungal ergosterol synthesis are used as antifungal marketers to deal with diverse fungal infections. These inhibitors target specific enzymes involved in the ergosterol biosynthesis pathway, disrupting the integrity of the fungal cell membrane and in the long run main to the demise of the fungus. One class of  antifungal tablets  that focus on ergosterol synthesis is the azole antifungals. Azoles inhibit the enzyme lanosterol 14α-demethylase, a cytochrome P450 enzyme that is important for the conversion of lanosterol to ergosterol. By inhibiting this enzyme, azoles disrupt the synthesis of ergosterol, leading to an accumulation of toxic sterol intermediates and causing membrane disorder. Here are a few examples of azole antifungals and their uses: Fluconazole : It is normally used to treat superficial and systemic fungal infections, such as ...