How Adalimumab helps treat Psoriasis and Psoriatic Arthritis

 Psoriasis and psoriatic arthritis are two distinct conditions that tend to occur collectively. However, psoriatic arthritis is often succeeded by psoriasis. Psoriasis is an autoimmune disease that causes rapid growth of the cells present in the skin. Psoriasis is denoted by red patches on the skin and white silvery scales on the elbows, knees, and lower back regions. Psoriasis and psoriatic arthritis occur as a result of an overreactive immune system. 

Psoriatic arthritis is one of the common types of autoimmune arthritis, where the body’s immune system mistakenly attacks the healthy body cells and causes inflammation of the joints. Studies have evaluated that almost 5-25% of psoriasis patients develop psoriatic arthritis. Psoriasis is the chief factor causing psoriatic arthritis. People with chronic psoriasis or untreated psoriasis are at a high risk of developing psoriatic arthritis. People with a genetic history of psoriasis or Psoriatic arthritis are at risk of developing the disease. Other risk factors that are associated with psoriatic arthritis include obesity and smoking.

Both psoriasis and psoriatic arthritis are life-altering diseases since they make individuals feel more disabled. The overwhelming inflammation is the only factor that causes psoriasis to develop into psoriatic arthritis. The most prominent indication of psoriatic arthritis is that it affects the joints on both sides of the body and causes intense pain in more than one joint. Psoriatic arthritis will be presented with severe joint pain with stiffness, swelling in the fingers and toes, terrible pain over the heels, lower backache, and tiny dents can appear in the nails. In some severe cases, inflammation can develop in the eyes causing visual changes accompanied by redness. 

If you have been enduring psoriasis or developed symptoms of psoriatic arthritis consult a rheumatologist immediately for medical support because psoriatic arthritis needs early onset treatment to prevent bone deformations. The rheumatologist can clinically confirm psoriatic arthritis after obtaining the X-ray and MRI reports to identify pitting bones. But initially, the doctor may perform a physical examination to analyze the joints and psoriatic lesions. Your doctor will also advise a blood test to check the inflammatory status, blood parameters such as ESR and CRP will be assessed because in psoriatic arthritis the levels of these inflammatory markers are elevated.

Primarily psoriatic arthritis will be treated with traditional medications that include pain killers, which help ease the pain, and disease-modifying agents that work by suppressing the immune system. For treating active psoriatic arthritis, your rheumatologist may prescribe you a combination therapy that includes disease-modifying agents and biologics. The drugs that come under biologics that are used in the treatment of psoriatic arthritis involve Adalimumab. You should maintain a logbook if you are on biological therapy since Adalimumab will be administered once every two weeks. Adalimumab is available as an injection and it is popularly uttered as Mabura 40 mg in the market. Mabura 40mg Injection is one such product that contains Adalimumab as the key constituent that works by binding to tumor necrosis factor (TNF). This protein is present in increased levels during inflammatory conditions. Thus, this medicine blocks the TNF, slows down the inflammation, and prevents flare-up of the disease.  It is suggested that you inform your doctor about your past medical history and allergies before taking Adalimumab to avoid any side effects. In addition to this, it is imperative to attend patient counseling sessions to prevent the relapse of psoriatic arthritis.